Ichthyosis treatment

Ichthyosis( crocodile skin, fish scales) - a rather rare, which is manifested in early childhood and runs a chronic hereditary anomaly of skin cornification

Causes

reasons that contribute to this disease are still not fully known, except that ichthyosis developedDue to gene mutation. Also of great importance are the deficiency in the body of vitamin A and endocrinopathies( hypofunction of sweat glands and thyroid gland).In the blood there is a large number of amino acids, as a result of which protein metabolism is disturbed, and because of the increased cholesterol content, fat metabolism is disrupted. These manifestations indicate a genetic malfunction and lead to the development of ichthyosis. Patients with this genetic mutation slows the metabolism is disturbed and thermoregulation

features and forms of ichthyosis

Currently there are several clinical forms of ichthyosis, which are caused by different groups of mutant genes.
The most common form is the

common ichthyosis .It manifests itself in early childhood and is inherited by an autosomal-dominant type. This form of ichthyosis is characterized by increased dryness of the skin and the formation of flakes on the skin grayish or whitish color, which in some severe cases, assume the form of coarse brown plates very dense touch. Unspoiled skin remains only in the folds and large skin folds. On the soles and palms, the skin lines are emphasized. Peeling skin on the face is usually insignificant. Sweating is markedly reduced. There may be a dystrophy of the hair and nail plates. Ordinary ichthyosis often combines with bronchial asthma, seborrheic eczema and atopic dermatitis .Congenital ichthyosis

quite pronounced even at birth, and is divided into ichthyosiform erythroderma and ichthyosis fetus( developing for 3-5 months pregnant and is rare).
When a child is born with an ichthyosis of the fetus, his skin is covered with thick horny layers that resemble a crocodile skin or tortoiseshell. Very often such children are premature and unviable.
When the newborn with ichthyosiform erythroderma, its skin is covered with a thin, dry, yellowish film, after which the rejection starts the so-called lamellar peeling whose degree with age only amplifies

Treatment

Depending on the severity of the disease, ichthyosis treated inpatient or outpatient. The patient is prescribed long, repeatedly repeated courses of vitamin A, B, E + vitamin C + nicotinic acid in high doses. To reduce the hardening of the scales, lipotropic preparations containing vitamin U and lipid are used. To strengthen immunity, the patient is recommended to take drugs with a high content of iron and calcium, as well as transfusion of blood plasma. In cases of lesion of the thyroid gland, it is recommended to take - thyroid, and in case of pancreatic damage - insulin. With congenital ichthyosis, or in especially severe cases, hormone therapy is prescribed. In terms
topical treatment of ichthyosis good effect on the patient provide trays with potassium permanganate and subsequent childhood skin treatment cream( salicylic petrolatum 1: 1 lanolin with vaseline oil, the oil concentrate retinol).In therapeutic doses, ultraviolet irradiation, carbon dioxide and sulphide baths, thallasotherapy are useful.